COMBINATION FORMULATIONS:
B-Complex Syrup (B1 HCl 5 mg, B2 2.5 mg, B6 HCl 1.5 mg, B12 5 mcg, Niacinamide 50mg, D-Panthenol 5 mg per 15ml)
B-Complex Tablets (B1 HCl 1 mg, B2 1 mg, Niacinamide 15mg)
PHARMACOKINETICS:-
Physiological amounts are absorbed by active transport. When large doses are given orally, some passive diffusion also occurs. Limited amts are stored in tissues. About 1 mg/day is degraded in body, excess is rapidly excreted in urine.
DEFICIENCY:-
Wet and Dry Beriberi.
THERAPEUTIC USES:-
- Prophylactically (2-10 mg daily) in infants, pregnant women, chronic diarrhea, patients on parentral alimentation.
- Beriberi
- In neurological and CV disorders, hyperemesis gravidarum, chronic anorexia and obstinate constipation.
ADVERSE EFFECTS:-
hiamine is nontoxic. Sensitivity reactions sometimes occur on parentral administration. |