Phenylbutazone Tablet USP Moa It Inhibits Cox And Is Potent Anti-Inflammatory Drug .It Inhibits Pg (Prostaglandin) Synthesis At Site Of Injury. Pharmocokinetics It Is Absorbed Orally; 98% Is Plasma Protein Bound And Completely Metabolized In Liver By Hydroxylation And Glucornidation. The Plasma T ½ Is 60 Hrs. Adverse Effects Nausea, Vomiting, Epigastric Distress And Peptic Ulceration, Diarrhoea. Uses In Severe Conditions Of Rheumatoid Arthritis And Spondylitis And Gout.